General Catalyst led U.S. startup funding in October by both deal count and capital deployed. The firm led or co-led at least nine known rounds and topped the spending list with $5.1 billion in aggregate value across its lead positions.

General Catalyst's largest deal was a $2.1 billion round for Re:Build, a startup that partners with manufacturers for product design and production. J.P. Morgan Asset Management co-led that financing. General Catalyst also participated in a $2 billion Series A for Axiom Solutions International, a cloud and power infrastructure spinout of manufacturing provider Flex, where Koch Equity co-led.

Lightspeed Venture Partners ranked second on the lead deal count with eight rounds, while Sequoia Capital and Andreessen Horowitz each led seven deals.

By total round participation across deals of $5 million or more, Y Combinator ranked as the busiest investor. Andreessen Horowitz participated in at least 22 qualifying rounds, followed by General Catalyst with 17.

Ramp, a fintech unicorn, closed a $1.9 billion Series G with five co-lead investors.

Venture investors participated in multiple rounds across October without major slowdown, though no single round matched earlier megafinancings for OpenAI and Anthropic.